赵培起,男,硕士研究生,主治医师。2008年毕业于河北北方学院,获医学学士学位;2011年毕业于天津医科大学,获
肿瘤学硕士学位。曾获得天津市王克昌奖学金、天津医科大学优秀硕士毕业生、天津市
肿瘤医院优秀硕士毕业生、天津市优秀硕士学位论文。本人自2011年供职于天津医科大学附属
肿瘤医院
肿瘤内一科(淋巴瘤
内科),从事乳腺癌、淋巴瘤、肺癌、消化系统
肿瘤的化疗及靶向治疗,具有丰富的临床经验。研究方向包括:纳米靶向药物制剂的研制及其在恶性
肿瘤诊治中的应用;多药耐药乳腺癌的发生、发展机制。本人作为主持人承担了国家自然科学基金、天津医科大学
肿瘤医院院级课题及天津医科大学自然基金各1项;除此之外还参与了863、国家自然科学基金、天津市科委和教委多项课题。共发表SCI及中文核心文章10余篇。发表文章:1 Peiqi Zhao, Hanjie Wang, Man Yu, Zhenyu Liao, Xianhuo Wang, Fei Zhang, Wei Ji, Bing Wu, Jinghua Han, Haichang Zhang, Huaqing Wang, Jin Chang, Ruifang Niu. Paclitaxel loaded folic acid targeted nanoparticles of mixed lipid-shell and polymer-core: In vitro and in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics 81 (2012) 248C256 )2.Jinghua Han , Fei Zhang , Man Yu , Peiqi Zhao, Wei Ji, Haichang Zhang, Bing Wu, Yuqing Wang, Ruifang Niu. RNA interference-mediated silencing of NANOG reduces cell proliferation and induces G0/G1 cell cycle arrest in breast cancer cells. Cancer Letters 321 (2012) 80C88 3.Bing Wu, Fei Zhang, Man Yu, Peiqi Zhao, Wei Ji, Haichang Zhang, Jinghua Han, Ruifang, Niu. Up-regulation of the Anxa2 gene Promotes Proliferation and Invasion of Breast Cancer MCF-7 cells. Cell Prolif., 2012, 45, 189C198 4.Hanjie Wang, Sheng Wang, Zhenyu Liao, Peiqi Zhao, Wenya Su, Ruifang Niu, Jin Chang. Folate-targeting magnetic coreCshell nanocarriers for selective drug release and imaging. International Journal of Pharmaceutics 430 (2012) 342C 3495.Zhenyu Liao, Hanjie Wang, Xiaodong Wang, Peiqi Zhao, Sheng Wang, Wenya Su,, Jin Chang. Multifunctional nanoparticles composed of a Poly( DL-lactide-coglycolide) core and a paramagnetic liposome shell for simultaneous Magnetic Resonance Imaging and targeted therapeutics. Advanced Functional Materials 2011, 21(6); 1179-1186. 6.Ruifang Niu, Peiqi Zhao, Hanjie Wang, Man Yu, Shuzhen Cao, Fei Zhang, Jin Chang. Preparation, characterization, and antitumor activity of paclitaxel-loaded folic acid modified and TAT peptide conjugated PEGylated polymeric liposomes. Journal of Drug Targeting, 2011; 19(5): 373C381 7.Zhenyu Liao, Hanjie Wang, Ruichun Lv, Peiqi Zhao, Xuezeng Sun, Sheng Wang, Wenya Su, Ruifang Niu, Jin Chang. Polymeric liposome-coated superparamagnetic iron oxide nanoparticles as contrast agent for targeted magnetic resonance imaging of cancer cells. Langmuir 2011; 27, 3100-31058.Peiqi Zhao, Hanjie Wang, Man Yu, Shuzhen Cao, Fei Zhang, Jin Chang, Ruifang Niu. Paclitaxel-loaded, folic-acid-targeted and TAT-peptide-conjugated polymeric liposomes: in vitro and in vivo evaluation. Pharmaceutical Research. 2010; 27(9):1914C1926. 9.Hanjie Wang, Peiqi Zhao, Wenya Su, Sheng Wang, Zhenyu Liao, Ruifang Niu, Jin Chang. PLGA/polymeric liposome for targeted drug and gene co-delivery. Biomaterials. 2010: 31: 8741-8748 10.Hanjie Wang, Peiqi Zhao, Xiaofei Liang, Tao Song, Xiaoqun Gong, Ruifang Niu, Jin Chang. Construction of a novel cationic polymeric liposomes formed from PEGlated octadecyl-quaternized lysine modi?ed chitosan/cholesterol for enhancing storage stability and cellular uptake ef?ciency. Biotechnology and Bioengineering. 2010; 106(6):952-62..11.Hanjie Wang, Peiqi Zhao, Xiaofei Liang, Xiaqun Gong, Tao Song, Ruifang Niu, Jin Chang. Folate-PEG coated cationic modi?ed chitosan C cholesterol liposomes for tumor-targeted drug delivery. Biomaterials. 2010; 31(14):4129C4138. 12.赵培起,曹淑贞,王汉杰,常津,牛瑞芳。HPLC检测紫杉醇高分子脂质体制剂的载药量和包封率。现代仪器,2010;16(3):27-29。13.李萌辉,张飞,郭华,张晓芳,赵培起,张宁,牛瑞芳。细胞运动抑制剂4-甲基-3-硝基-苯甲酸的基础研究。中国
肿瘤临床,2010;37(11):601-604。14.曹淑珍,张飞,赵培起,韩敬华,武冰,张海嫦,张霖,牛瑞芳。Annexin a2表达对人乳腺癌细胞增殖、迁移和侵袭能力的影响。中国
肿瘤临床2011; 38(6): 304-307。15.曹淑珍,张飞,赵培起,魏希胤,杨毅,牛瑞芳。Annexin a2对人乳腺癌MDA-MB-231增值的影响及分子机。山东医药, 2010; 51(12): 26-29。