王柯，医学博士，硕士研究生导师，美国UCLA访问学者。1996-2001年，复旦大学医学院（原上海医科大学）2001-2005年，复旦大学附属中山医院2005-2010年，复旦大学附属华山医院神经
外科2012-2013年，美国加州大学洛杉矶分校Ronald Reagan医学中心神经
外科从事临床工作十余年，对脑外伤、脑卒中等神经科危重病人的治疗积累了一定的经验。熟悉脑胶质瘤、听神经瘤、垂体瘤和脊髓
肿瘤等各类
中枢神经系统
肿瘤的手术治疗；同时开展各类神经病理性疼痛、难治性癫痫等功能性神经系统疾病的手术治疗。基础科学研究以脑胶质瘤的信号通路为主要方向，主持一项国家自然科学基金课题和一项上海市级课题研究。临床研究重点为各类神经科危重患者的手术治疗及围手术期处理，主持自发性脑出血手术治疗的临床研究，在国外知名期刊发表多篇学术论文。1. Wang K, Sun J, Zhang X, Zhang Q, Chen Z. Management of consecutive development of ruptured intracranial mycotic aneurysms. Case report. Turk Neurosurg 2015, 25(2):310-312.2. Wang K, Du HG, Yin LC, He M, Hao BL, Chen L. Which side of lateral ventricles to choose during external ventricular drainage in patients with intraventricular hemorrhage: ipsilateral or contralateral? Journal of Surgical Research, 2013;183:720-5. 3. Wang K, Liu Z, Chen X, Lou M, Yin J. Clinical characteristics and outcomes of patients with cerebral herniation during continuous lumbar drainage. Turk Neurosurg, 2013; 23(5): 653-7.4. Wang K, Xue Y, Chen XZ, Zhou B, Lou M. Uncorrected traumatic coagulopathy is associated with severe brain swelling during decompressive surgery to evacuate a supratentorial intradural mass lesion in patients with traumatic brain injury. Neurological Research, 2013, 35(6):642-648.5. Lou M, Chen XZ,Wang K*, Xue YJ, Cui DM, Xue F. Increased intracranial pressure is associated with the development of acute lung injury following severe traumatic brain injury.Clinical Neurology and Neurosurgery, 2013, 115(7): 904-908.6. Lou M, Xue Y, Xue Fei, Chen L, Wang K*. Is high PEEP ventilation strategy safe for acute respiratory distress syndrome after severe traumatic brain injury? Brain Injury, 2012, 26(6):887-890.7. Wang K, Xue Y, Chen X, Cui D, Lou M. Transtentorial herniation in patients with hypertensive putaminal haemorrhage is predictive of elevated intracranial pressure following haematoma removal. J Clin Neurosci, 2012,19:975-979.8. Wang K, Pan L, Che X, Lou M. Gamma knife surgery-induced ependymoma after the treatment of meningioma. a case report. Neurol Neurochir Pol, 2012, 3:294-296.9. Wang K, Pan L, Che X, Cui D, Li C. Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines. J Neurooncol, 2010, 98(3):319-327.10. Wang K, Pan L, Che X, Cui D, Li C. Sonic Hedgehog/GLI signaling pathway inhibition restricts cell migration and invasion in human gliomas. Neurol Res, 2010, 32(9):975-980.
