王树森主任医师
中山大学附属肿瘤医院 肿瘤内科
擅长
乳腺癌的化学治疗、内分泌治疗及靶向治疗
简介
王树森,男,中山大学肿瘤医院内科乳腺病区主任、主任医师、医学博士、硕士生导师。2004年毕业于中山大学,获肿瘤学博士学位。2010年在Memorial Sloan-Keterring Cancer Center学习。现在主要从事乳腺癌的化疗、内分泌治疗及靶向治疗。社会兼职:中国抗癌协会肿瘤临床化疗专业委员会青委会副主任委员、中国医药教育协会乳腺癌专业委员会常务委员、中国老年肿瘤专业委员会乳腺癌分委会常务委员、中国抗肿瘤药物安全管理专家委员会委员、中国抗癌协会肉瘤专业委员会化疗学组委员、海峡两岸医药卫生交流协会肿瘤防治专家委员乳腺肿瘤专业学组常委、广东省医师协会乳腺专科工作委员会副主任委员、广东省抗癌协会化疗专业委员会副主任委员、广东省胸部肿瘤防治研究会副会长、广东省健康管理协会乳腺癌专业委员会副主任委员、广东医学会乳腺癌专业委员会青委会副主任委员主要研究方向: 乳腺癌的化学治疗、内分泌治疗及靶向治疗专家门诊时间:周一上午、周四上午论著(近5年发表作为的主要论文):1. Wangbing Chen(#), Lijun Qin(#), Shusen Wang(*), Mei Li, Dingbo Shi, Yun Tian, Jingshu Wang, Lingyi Fu, Zhenglin Li, Wei Guo, Wendan Yu, Yuhui Yuan, Tiebang Kang, Wenlin Huang(*) and Wuguo Deng(*), CPSF4 activates telomerase reverse transcriptase and predicts poor prognosis in human lung adenocarcinomas. Molecular Oncology, 2014, 8(3):704-716.(共同通讯) (IF:6.701)2. Lingyi Fu(#), Ke Shi(#), Jingshu Wang, Wangbing Chen, Dingbo Shi, Yun Tian, Wei Guo, Wendan Yu, Xiangsheng Xiao, Tiebang Kang, Shusen Wang(*), Wenlin Huang(*) and Wuguo Deng(*), TFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signaling. Molecular Cancer, 2014, 13:89.(共同通讯) (IF:5.397)3. Wangbing Chen(#), Jianjun Lu(#), Yun Qin(#), Jingshu Wang(#), Yun Tian, Dingbo Shi, Shusen Wang(*), Yao Xiao, Meng Dai, Lu Liu, Guo Wei, Taihua Wu, Bliian Jin(*), Xiangsheng Xiao, Tiebang Kang, Wenlin Huang and Wuguo Deng(*), Ret finger protein-like 3 promotes tumor cell growth by activating telomerase reverse transcriptase expression in human lung cancer cells. Oncotarget, 2014, 5(23):11909-11923.(共同通讯) (IF:6.627)4. 杨燕华(#), 王树森(*). 乳腺癌中TOP2A与蒽环类药物关系的研究进展. 中国普外基础与临床杂志 2014; 21(8): 1029-1033.5. 夏雯(#), 王树森(*). 依维莫司相关口腔炎研究进展. 中国新药杂志 2014; 23(24): 2933-2937.6. 曾银朵(#), 徐菲, 覃涛, 杨燕华, 廖玉婷, 秦歌, 王树森(*), 托瑞米芬治疗绝经后可手术luminal型乳腺癌的疗效观察. 中国普外基础与临床杂志 2014; 21(5):555-561.7. 马宏民(#), 胡玲玉, 王树森(*), 隐匿性乳腺癌的诊断与治疗. 中国普外基础与临床杂志 2014;21(5): 544-548.8. Lingyi Fu(#), Wangbing Chen(#), Wei Guo, Jingshu Wang, Yun Tian, Dingbo Shi, Xiaohong Zhang, Huijuan Qiu, Xiangsheng Xiao, Tiebang Kang, Wenlin Huang, Shusen Wang(*) and Wuguo Deng(*), Berberine Targets AP-2/hTERT, NF-κB/COX-2, HIF-1α/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth. PLoS One, 2013, 8(7):e69240.(共同通讯) (IF:3.73)9. Tao Qin(#), Zhongyu Yuan(#), Roujun Peng, Yinduo Zeng, Yanxia Shi, Xiaoyu Teng, Donggeng Liu, Bing Bai and Shusen Wang(*), Efficacy and tolerability of toremifene and tamoxifen therapy in premenopausal patients with operable breast cancer: a retrospective analysis. Current Oncology, 2013, 20(4):196-204. (通讯作者) (IF:1.625)10. Tao Qin(#), Zhongyu Yuan(#), Roujun Peng, Bing Bai, Yanxia Shi, Xiaoyu Teng, Donggeng Liu and Shusen Wang(*), HER2-positive breast cancer patients receiving trastuzumab treatment obtain prognosis comparable with that of HER2-negative breast cancer patients. Onco Targets Ther, 2013, 6:341-347.(通讯作者) (IF:2.073)11. Wangbing Chen(#), Wei Guo(#), Mei Li, Dingbo Shi, Yun Tian, Zhenlin Li, Jingshu Wang, Lingyi Fu, Xiangsheng Xiao, Quentin Qiang Liu, Shusen Wang(*), Wenlin Huang and Wuguo Deng(*), Upregulation of Cleavage and Polyadenylation Specific Factor 4 in Lung Adenocarcinoma and Its Critical Role for Cancer Cell Survival and Proliferation. PLoS One, 2013, 8(12):e82728. (共同通讯) (IF:3.73)12. Wei-Guang Gu(#), Yan Huang(#), Zhong-Yu Yuan, Rou-Jun Peng, Hai-Tao Luo, Zhi-Ren He and Shu-Sen Wang(*), ZD1839 and Cisplatin Alone or in Combination for Treatment of a Nasopharyngeal Carcinoma Cell Line and Xenografts. Asian Pacific Journal of Cancer Prevention, 2013, 14(3):1787-1790.(通讯作者) (IF:1.24)13. 胡夕春, Di Leo Angelo, 王晓稼, 王树森, 蔡莉, 邸立军, 滕月娥, 王碧芸, 朱丽, 黎莉, 王佳玉. Luminal型晚期乳腺癌的共识和争议. 中华乳腺病杂志(电子版) 2013; 7(2):76-79.14. 覃涛(#), 袁中玉, 彭柔君, 白冰, 史艳侠, 滕小玉,刘冬耕,王树森(*),托瑞米芬治疗Luminal型年轻乳腺癌疗效和安全性的回顾性研究. 中山大学学报(医学科学版),2013;34:402-406.15. 王树森(#), 任重阳. 依维莫司可用于治疗激素受体阳性的绝经后晚期乳腺癌患者. 循证医学 2013; 13(3):141-143.16. Shusen Wang(#), Yanxia Shi, Zhongyu Yuan(*), Xi Wang(*), Donggen Liu, Roujun Peng, Xiaoyu Teng, Tao Qin, Jiewen Peng, Guinan Lin and Xiaomei Jiang, Classical CMF regimen as adjuvant chemotherapy for triple-negative breast cancer may be more effective compared with anthracycline or taxane-based regimens. Medical Oncology, 2012, 29(2):547-553.(第一作者) (IF: 2.21)17. Jiehua He(#), Roujun Peng(#), Zhongyu Yuan(*), Shusen Wang, Jiewen Peng, Guinan Lin, Xiaomei Jiang, Tao Qin. Prognostic value of androgen receptor expression in operable triple-negative breast cancer: a retrospective analysis based on a tissue microarray. Med Oncol 2012;29:406-410.18. Donggen Liu, Jiehua He, Zhongyu Yuan, Shusen Wang, Roujun Peng, Yanxia Shi et al. EGFR expression correlates with decreased disease-free survival in triple-negative breast cancer: a retrospective analysis based on a tissue microarray. Med Oncol 2012;29:401-405.19. Roujun Peng(#), Shusen Wang(#), Yanxia Shi, Donggen Liu, Xiaoyu Teng, Tao Qin, Yixin Zeng(*) and Zhongyu Yuan(*), Patients 35 years old or younger with operable breast cancer are more at risk for relapse and survival: A retrospective matched caseCcontrol study. The Breast, 2011, 20(6):568-573.(共同第一) (IF:2.58)20. Cong Xue(#), Xi Wang(#), Roujun Peng, Yanxia Shi, Tao Qin, Donggen Liu, Xiaoyu Teng, Shusen Wang, Li Zhang(*) and Zhongyu Yuan(*). Distribution, clinicopathologic features and survival of breast cancer subtypes in Southern China. Cancer Sci 2012;103:1679-1687.21. Bing Bai(#), Zhongyu Yuan, Donggeng Liu, Xiaoyu Teng, Shusen Wang(*). Clinical features and survival analysis of different subtypes of patients with breast cancer brain metastases. Chin J Cancer 2010;29:413-9.(通讯作者)22. 王曦(#), 王树森(#), 刘鹏, 唐军, 袁中玉(*). 125例乳腺浸润性小叶癌的临床特征及预后分析. 肿瘤研究与临床 2010;22(8):550-553.基 金(正在主持的包括国家自然科学基金、广东省自然科学基金以及广东省科委等如下科研项目):(1)乳腺癌hTERT调控因子的垂钓鉴定及其在乳腺癌发生发展中的作用及机制(2)AP-2β对hTERT 基因的转录调控及其对乳腺癌诊治价值的探讨(3)氟维司群用于绝经后激素受体阳性乳腺癌患者一线治疗后维持治疗的疗效及安全性的多中心、前瞻性研究(4)靶向Her2的药物治疗Her2阳性乳腺癌的耐药机制研究(5)CPSF4在乳腺癌HER2/PI3K/AKT信号传导通路中的作用及机制科研成果:  表皮生长因子受体酪氨酸激酶抑制剂ZD1839对鼻咽癌作用的实验研究,被评为第三届全国肿瘤大会优秀论文。