喉接触性肉芽肿治疗确实棘手,目前公认的方法是抑制胃酸分泌,但是仍有个别患者效果不理想,最近文献报告的两种治疗方法分享给大家:
1、肉芽肿局部激素注射治疗:表麻下局部注射曲安奈德(40 mg/mL)0.3-0.5ml,每月一次,三个月复查,10例患者中6例全部消失,4例仅少许残留。(Wang CT, et al. Intralesional Steroid Injection: An Alternative Treatment Option for Vocal Process Granuloma in Ten Patients. Clinical Otolaryngology, 09/14/2012, online)
2、手术加放疗:手术切除后马上三维适形放疗5天15Gy,15例患者无一例复发。(Song Y, et al.Surgical removal followed by radiotherapy for refractory vocal process granuloma. J Voice, 2012,26(5):666.e1-5.)
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