陈振光主任医师
中山大学附属第一医院 胸外科
擅长
从事专业二十年,擅长肺脏、食管、纵膈、胸腺外科的常见病、疑难病如肺癌、食管癌、支气管扩张、重症肌无力、漏斗胸等的外科治疗和微创治疗,胸部肿瘤的化疗和靶向治疗。
简介
陈振光,医学博士,中山一院胸外科主任医师、硕士生导师,中山一院东院院长助理、心胸外科主任,兼任欧洲临床肿瘤学会 (ESMO) 会员,中国医师协会胸外科分会委员,广东省医院协会第九届理事,广东省医院协会肿瘤防治管理分会秘书长及胸部肿瘤专业委员会副主任委员,广东省医学会细胞治疗学分会常委,广东省医学会胸外科学会委员,广东省医师协会胸外科分会委员,广东省医疗行业协会胸外科分会常委,广州东部医学论坛秘书长及呼吸专业委员会副主任委员,广州市医学会中青年学术研究会常委,国家自然科学基金评审专家,广东省自然科学基金评审专家,《中国组织工程与临床康复杂志》执行编委, Medicine(IF 5. 7)、BMC Cancer (IF 3.3)、PLOS On(IF 3. 2)、Thorac Cancer(IF 1.1)、J Cardiothorac Surg(IF 1. 0)、Clinical Medical Insights: Oncology、Cell Proliferation、J Solid Tumor、Chinese Med J-Peking(IF 1.601)等杂志审稿专家。主要研究方向为肺癌的分子发病机制和治疗以及重症肌无力的外科治疗。曾在2nd European Lung Cancer Conference (ELCC, Geneva) 大会发言,并获得Travel Award of 2nd European Lung Cancer Conference (ELCC, Geneva)和Travel Award of 35th European Society for Medical Oncology (ESMO,Milan),已发表论文近60篇,并在Ann Oncol (IF 7.0)、Oncotarget (IF 6.4)、Medicine (IF 5.7)、Ann Thorac Surg (IF 3.8)、Eur J Cardiothorac Surg (IF 3.3)、PLoS One (IF 3.2)、J Thorac Oncol (IF 5.3)、Hum Pathol (IF 2.8)、J Exp Clin Cancer Res (IF 4.4)、Cancer Cell International (IF 2.8)、Med Oncol (IF 2.6)、J Cardiothorac Surg (IF 1.0)、J Int Med Res (IF 1.4)等SCI杂志发表论文近30篇,总影响因子74.5。 已发表论文: 1. Relationship of Oct-4 to malignant stage: a meta-analysis based on 502 positive/high Oct-4 cases and 522 negative/low case-free controls. Zhong B, Lin Y, Lai Y, Zhen ng X, Huang R, Yang W, Chen Z (通讯作者). Oncotarget. 2015 Nov 9. doi: 10.18632/oncotarget.5737. [Epub ahead of print] IF 6.4 2. Chen Z(通讯作者), Zhong B, Lun X, Lai Y, Bella AE, Yang W, Wu J. Specific Safety Profile of Bevacizumab in Asian Patients With Advanced NSCLC: A Meta-Analysis. Medicine (Baltimore). 2015 Jun; 94(24):e975. IF 5.7 3. Association of the intermediate filament nestin with cancer stage: a meta-analysis based on 223 positive/high nestin cases and 460 negative/low case-free controls. Zhong B, Wang T, Zou J, Zheng F, Huang R, Zheng X, Yang W, Chen Z(通讯作者). Oncotarget. 2015 May 8, Vol 6, No 26: 22970-22977. IF 6.4 4. Wang T, Yang W, Li W, Xiang AP, Chen Z (通讯作者). Contribution of mesenchymal stem cells (MSCs) on epithelial-mesenchymal transition (EMT) of esophageal squamous cell carcinoma. Poster presentation at European Society for Medical Oncology (ESMO) 2014 Congress, Madrid, Spain (No. 157P). 5. Chen Z (通讯作者), Zhong B, Wang T, Yang W, Li W, Xiang AP. Nestin promotes proliferation and apoptosis and correlates with poor prognosis in esophageal squamous cell carcinoma. Poster presentation at European Society for Medical Oncology (ESMO) 2014 Congress, Madrid, Spain (No. 219P). 6. Yang W, Chen Z (通讯作者), Wang T, Li W, Xiang AP. Clinicalpathological characteristics of cancer-associated-fibroblast in esophageal squamous cell carcinoma. Poster presentation at European Society for Medical Oncology (ESMO) 2014 Congress, Madrid, Spain (No. 1594P). 7. Chen Z (通讯作者),Wang Tao, et al. Stem cell marker nestin expression correlates with proliferation and cell cycle in non-small cell lung cancer. Poster presentation at 35th European Society for Medical Oncology (ESMO) Congress, Milan, 2010, Italy (No. 1594P). Travel Award of European Society for Medical Oncology (ESMO, Milan, 2010). 8. Chen Z (通讯作者), Wang T, Luo H, Yang X, Hao Y, Su C, Lei Y, Li F, Pan H, Zhang X, Lahn BT, Xiang AP. Nestin expression in non-small cell lung cancer and its relevance with prognostic significance. Oral presentation at 2nd European Lung Cancer Conference (ELCC, Geneva, 2010, No. 910). Travel Award of 2nd European Lung Cancer Conference (ELCC, Geneva, 2010) 10. Beilong Zhong, Chen Zhenguang (通讯作者), et al. Contribution of nestin positive esophageal squamous cancer cells on malignant proliferation, apoptosis, and poor prognosis. Cancer Cell International 2014, 14: 57. IF 2.8 11. Chen Zhenguang (通讯作者),Wang Jianjun, et al. Role of the stem cell-associated intermediate filament nestin in malignant proliferation of non-small cell lung cancer. PLoS One 2014 Feb 3; 9(2): e85584. doi: 10.1371/journal.pone.0085584. eCollection 2014. IF 3.2 12. Chen Zhenguang (通讯作者),Zuo Jidong, et al. Cellular immunity following video-assisted thoracoscopic and open resection for non-thymomatous myasthenia gravis. Eur J Cardiothorac Surg 2014, Apr, 45(4): 646-651. IF 3.3 13. Liu Zhaoguo, Lei Yiyan, Chen Zhenguang (通讯作者), et al. The co-expression of ERβ2 and IL-12Rβ2 is better prognostic factor in non-small-cell lung cancer progression. Med Oncol 2013; 30(3): 592. doi: 10.1007/s12032-013-0592-x. IF 2.6 14. Chen Zhenguang (通讯作者),Wang Tao, et al. Nestin expression in non-small cell lung cancer and its relevance with prognostic significance. J Thorac Oncol 2010, 5 (Suppl 1): S39. IF 5. 3 15. Chen Zhenguang (通讯作者),Wang Tao, et al. Stem cell marker nestin expression correlates with proliferation and cell cycle in non-small cell lung cancer. Ann Oncol 2010, 21 (Suppl 8): viii130. IF 7.0 16. Chen Zhenguang (通讯作者),Wang Tao, Luo Honghe, et al. Expression of nestin regarding to lymph node metastasis and lymphangiogenesis in non-small cell lung cancer patients. Hum Pathol 2010, 41: 737-744. IF 2.8 17. Chen Zhenguang (通讯作者),Pan Hongxin, Wang Tao, et al. Primary thymic seminoma in a 32-year-old female. Ann Oncol 2010, May; 21(5): 1132-4. IF 7.0 18. Chen Zhenguang (通讯作者),Wang Tao, Cai Lie, et al. Clinicopathological significance of non-small cell lung cancer with high prevalence of Oct-4 tumor cells. J Exp Clin Cancer Res 2012, 31: 10. IF 4.4 17. Chen Zhenguang (通讯作者), Luo Honghe, Peng Yanwen, et al. Comparative clinical features and immune responses after extended thymectomy for myasthenia gravis in patients with atrophic versus hyperplastic thymus. Ann Thorac Surg 2011, Jan; 91(1): 212-218. IF 3.8 18. Su Chunhua, Luo honghe, Chen Zhenguang (通讯作者), et al. Different patterns of NF-κB and Notch1 signaling contribute to tumor-induced lymphangiogenesis of esophageal squamous cell carcinoma. J Exp Clin Cancer Res 2011, 30: 85. IF 4.4 19. Luo Honghe, Chen Zhenguang (通讯作者), Jin Hui, et al. Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer. J Exp Clin Cancer Res 2011, Jan10; 30(1): 6. IF 4.4 20. Chen Zhenguang (通讯作者) , Luo Honghe, Zhuang Mei, et al. Effects of ischemic preconditioning on ischemia/reperfusion-induced arrhythmias by upregulatation of connexin 43 expression. J Cardiothorac Surg 2011; 6:80. IF 1.0 21. Chen Zhenguang (通讯作者), Amos Ela Bella, Luo Honghe, et al. Comparative pulmonary functional recovery after Nuss and Ravitch procedures for pectus excavatum repair: a meta-analysis. J Cardiothorac Surg 2012; 7: 101. IF 1.0 22. Su Chunhua, Su Yihua, Chen Zhenguang (通讯作者), et al. Intravenous flurbiprofen for post-thymectomy pain relief in patients with myasthenia gravis. J Cardiothorac Surg 2012; 7: 98. IF 1.0 23. Luo Honghe, Lei Yiyan, Chen Zhenguang (通讯作者), et al. Primary cardiac osteosarcoma in a 42-year-old woman. J Cardiothorac Surg 2010, 27; 5: 120. IF 1.0 24. Clinical outcome and predictive factors of irradiation-associated myasthenia gravis exacerbation in thymomatous patients. Li Y, Chen P, Ding L, Luo C, Wang H, Chen Z, Su C, Feng H, Huang X, Xia W, Liu W. Neurol Sci. 2015 Nov;36(11):2121-7. doi: 10.1007/s10072-015-2325-8. Epub 2015 Jul 26. 25. Zou Jianyong, Amos Ela Bella, Chen Zhenguang, et al. Frequency of EGFR mutations in lung adenocarcinoma with malignant pleural effusion: Implication of cancer biological behaviour regulated by EGFR mutation. J Int Med Res 2014 Oct; 42(5): 1110-7. doi: 10.1177/0300060514539273. IF 1.4 26. 同种移植大鼠心脏II类主要组织相容性抗原表达及其机制探讨。中华心血管病杂志,2003,Vol 31, No 2。 27.移植心Th细胞免疫偏离与MHC II类抗原表达的关系。中国病理生理杂志,2002,6,18(6)。 28. 小体重大鼠供心移植模型的建立和MHC II类抗原的分布。中华实验外科杂志,2001,12,18(增刊) 29. 严重闭合性胸外伤30例的并发症诊治体会。新医学,2001,32(5)。 30. 血管通路比例对大鼠颈部心脏移植模型的影响。中山医科大学学报,2001,22(2)。 31. 大鼠移植心心电图改变与急性排斥相关关系。中山医科大学学报,2001,22(4)。 32. 心脏移植急性免疫排斥反应的研究进展。新医学,2001,6,32。 33. 心脏直视手术中的心肌保护。新医学,2005,7,36(7)。