In one meta-analysis of 16 case-contol studies who underwent esophagectomy, open resection was compared to minimally invasive esophagectomy. Oncologic efficacy (lymph node dissection) and survival were similar between the surgical techniques.

In one randomized study in 5 centers: the incidence of pulmonary infections was reduced by over 50% in the MIE（Miminal invasive esophagectomy） group, whereas other outcomes were similar.河南省肿瘤医院胸外科李进东